Employer: UCSD
Website: http://frazer.ucsd.edu
Location: La Jolla
Type: Postdoctoral
Posted: October 10, 2011
Expires: November 18, 2011
Jobs by tag(s): san diego genomics bioinformatics molecular biology sequencing genetics variants snp ipsc regulation transcription chromatin
Requisition number: FUNGEN_GIS
job description
Department: Pediatrics, Division of Genome Information Science
Position Title: Postdoctoral Research Associate
Description: The division of Genome Information Science is applying genomic methods and analysis strategies to identify and annotate regulatory DNA variants in the human genome. Our research is highly collaborative as we perform team science involving several basic and clinical collaborators from the UCSD School of Medicine. The division is equipped with Next Generation Sequencing technology and state of the art computational resources. It directly benefits from the highly competitive genomic and bioinformatics environment of UCSD and the San Diego biotech community.

We are seeking a postdoctoral candidate with interest in chromatin and transcriptional regulation who wishes to further develop their understanding of the molecular interplay between DNA variants and gene expression. Studying iPS derived cells and using state of the art genomic approaches, the candidate will decipher the influence of DNA variation on gene expression in the whole genome as well as few selected genomic loci.

Qualifications:
• PhD (+0-3 years experience) in genomics, molecular biology or related field.
• Demonstrated experience with molecular biology techniques such as ChIP, ChIP-Seq, RNA-Seq, qPCR, 3C, reporter assays
• Familiar with mammalian cell culture, transfection assays and FISH
• Experience with Next Generation Sequencing protocols
• Solid knowledge of public genomic databases, queries and analysis (UCSC Genome Browser, BioMart, ENSEMBL)
• Advanced knowledge of Excel or, more desirable, familiar with Linux operating system and one programming language (Perl, Python, R, awk)
• Demonstrated successful, positive interpersonal, oral and written communication skills.
• Well organized and detail oriented

Salary will be commensurate with experience and based on NIH Postdoctoral recommended salary scales adjusted for qualifications and experience.

To Apply: Applications should include cover letter, detailed curriculum vitae and the names, addresses, e-mail addresses and phone numbers of at least two referees. Please submit materials to Olivier Harismendy, PhD. oharismendy@ucsd.edu